Variations in hepatic lipid species of age-matched male mice fed a methionine-choline-deficient diet and housed in different animal facilities

Abstract Background Non-alcoholic steatohepatitis (NASH) is a common disease and feeding mice a methionine-choline-deficient (MCD) diet is a frequently used model to study its pathophysiology.Genetic and environmental factors influence NASH development and liver lipid content, which was studied herein using C57BL/6 J mice bred in two different anim

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Bone Regeneration: Mini-Review and Appealing Perspectives

Bone is a natural mineral-organic nanocomposite protecting internal organs and allowing mobility.Through the ages, numerous strategies have been developed for repairing bone defects and fixing fractures.Several generations of bone repair biomaterials have been proposed, either based on metals, ceramics, glasses, or polymers, depending on the clinic

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Inducing vulnerability to InhA inhibition restores isoniazid susceptibility in drug-resistant Mycobacterium tuberculosis

ABSTRACT Of the approximately 10 million cases of Mycobacterium tuberculosis (Mtb) infections each year, over 10% are resistant to the frontline antibiotic isoniazid (INH).INH resistance is predominantly caused by mutations that decrease the activity of the bacterial enzyme KatG, which mediates the conversion of the pro-drug INH to its active form

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CRIMINAL OFFENSES AGAINST BANKRUPTCY DEBTORS WHO DO NOT ACT IN GOOD FAITH TOWARDS THE MANAGEMENT AND ADMINISTRATION OF BANKRUPTCY ESTATE TO ENSURE LEGAL CERTAINTY

Debtors who Delaware are not in good faith will make every effort to avoid bankruptcy in the PKPU process and also do not have good faith to carry out their debt payment obligations if declared bankrupt, the debtor has the potential to take actions that are not compliant with the bankruptcy decision and are not cooperative with the duties of curato

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